Hi, ophthalmologist here :-) The good news is that if there is no underlying pathology (such as keratoconus, which should be sought in case of progressing astigmatism), every ametropia can be corrected with the right glasses and allow a good working comfort.

First, check your prescription with an ophthalmologist (or optometrist, depending on your country). You may benefit from a cycloplegic refraction, to ensure that you don't have an undercorrected hyperopia.

Then, always wear your glasses when working.

Your floaters don't have a direct relationship with your astigmatism and you may need a fundus examination, which will be done at the same time as your cycloplegic refraction (pupils will be dilated using eye drops).

Reducing the screen light and using a blue filter may also help. But good prescription is key.