Same! I live in this ecosystem (Atom + Hydrogen python sessions) on a daily basis. But rather than for "science", i use it for devops productivity (scrape logs, query dbs, automate mitigations) and some low-key data analysis.

It's breathed life into my love for programming, given how easy it is to just start executing code (sometimes I just use it as a calculator app since it's that easy and accessible)

I tried VSCode's equivalent plugin, but the UX was nowhere near as nice.