Most of it, but there are some corners. For example, high temperature superconductivity was discovered in 1986 [1]. The process is not so complicated, and can be done at home. Well, at least in a very good personal lab, for example see this video by Applied Science. https://www.youtube.com/watch?v=sLFaa6RPJIU

I think the original team made like 100 samples using different metals and different oxygen proportion. Discovering the first one requires some brute force that needs a small team, and is too much for a single person. Anyway, it doesn't look too far away from something a single person can discover.

[1] That's 36 year ago. I'm feeling old...