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A comment on Remote Work Is Gutting Downtowns, Will Cost Cities $453B. Parent comment

Re:Remote Work Is Gutting Downtowns, Will Cost Cities $453B by lamontcg on Tuesday December 06, 2022 @02:10PM (#33885384)
> However, the "initial viral load" is much smaller, giving your body more time to mount an effective defense.

That's a myth from the early pandemic. Viral dose doesn't correlate with disease severity:

https://medicalxpress.com/news/2021-11-relationship-viral-do...

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Re:Remote Work Is Gutting Downtowns, Will Cost Cities $453B by amanaplanacanal on Tuesday December 06, 2022 @02:55PM (#33886107)
But:

the likelihood of becoming infected may rise with the size of that "dose."

So a small dose might still prime the immune system even if you don't get sick.

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Re:Remote Work Is Gutting Downtowns, Will Cost Cities $453B by lamontcg on Tuesday December 06, 2022 @08:13PM (#33889489)
> the likelihood of becoming infected may rise with the size of that "dose."

This is correct.

> So a small dose might still prime the immune system even if you don't get sick.

This does not follow.

If you don't get infected following a small dose, you'll have fought it off with your innane or intrinsic defenses. You won't generate any humoral immunity, form T-cells or B-cells or neutralizing antibodies and won't be any better off for the next round with the virus.

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