I use Ocullus quest 2 to play (and LOVE it!). Weight, head and neck strain / tightness are the first issue. Nausea is the follow up. Eye strain is the final. I never use it for more than 30min at the time.

I cannot imagine spending ANY work time in VR at this point in technology cycle, once you add resolution, accuracy, etc. I do not understand what problem it's solving - if you want to visually interact remotely, turn on your camera. If you don't, just talk and screenshare. I do not understand what virtual reality will add to my interactions and productivity.