Amygdala connectivity predicts ketamine treatment response among patients (cont)

Re:Amygdala connectivity predicts ketamine treatment respons... by DontchaKnowit on Monday November 28, 2022 @12:09PM (#33776213)

I dont understand why we arent looking into methoxetamine over ketamine. Or any of the derivatives with a stronger dose-response curve. DCK, O-PCE, etc. These all have similar chemical and psychoactive properties and the doses are orders of magnitude smaller ergo they dont completepy fuck your bladder up.

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Re:Amygdala connectivity predicts ketamine treatment respons... by jonnycomputer on Monday November 28, 2022 @12:13PM (#33776269)

>I dont understand why we arent looking into methoxetamine over ketamine.

Seems like we are.

https://scholar.google.com/scholar?start=10&q=methoxetamine+...

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Re:Amygdala connectivity predicts ketamine treatment respons... by chimeracoder on Monday November 28, 2022 @02:34PM (#33778422)

> the doses are orders of magnitude smaller ergo they dont completepy fuck your bladder up.

There is zero clinical evidence of bladder damage due to ketamine in the amounts used for clinical purposes.

Yes, there is evidence for bladder damage in heavy, chronic users, but none of that has been shown in therapeutic schedules, and there is very strong evidence against the existence of any such link in therapeutic schedules.

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