I mentioned Rails because Django and Rails are extremely similar as they try to solve the same problem with similar approaches. The differences in how the two work come down to philosophy. Rails trades a lot more simplicity for ease of use with its "convention over configuration" approach. Django chooses more simplicity over ease of use.

If I were to diagram those two and Node.js, I'd say it looks like this:

Easy <---------------------------> Simple

Rails <-------> Django <------> Node.js