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Re:My ADHD Founder Toolbox by hirvi74 on Saturday November 19, 2022 @02:09AM (#33667814)
I've been on the medications for almost a decade now, so when I take a weekend off, then I am basically useless by Monday when I start them again. I swear it takes days from them to start working again every time I take a break.

So, my dopaminergic system probably has holes burned through it.

Re:My ADHD Founder Toolbox by sph on Saturday November 19, 2022 @02:01PM (#33673410)
Yes, I have certainly noticed it takes a few days for the full effect to ramp up as well. And there seems to be residual effect for about 12 hours after the last dose, though in general the peak effect lasts about 4 hours for me (on lisdexamphetamine)