IMO the reason Holmes deserves to be locked up for a long time is not just because of the fraud she committed, but the way she tried to use her power and her powerful friends to destroy people whose only crime was telling the truth.

Seriously, read Bad Blood, see what she tried to do to Tyler Schultz, Erika Cheung, and Rochelle Gibbons (the widow of the Theranos scientist that committed suicide), among many others. The best analogy I can think of is Lance Armstrong's fraud. Yes, his cheating and lying about it was bad, but I guess at least somewhat understandable given the culture of cycling at the time. But the reason I despise the man is due to his mafioso tactics of intimidation he used to silence people. Holmes did the exact same.