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Re:Nicotinamide riboside uptake linked to metastasis and NAD... by bookofjoe on Monday November 14, 2022 @02:36PM (#33599685)
>Popular vitamin supplement carries increased cancer risk, scientists warn

https://studyfinds.org/nicotinamide-riboside-vitamin-b3-supp...

Re:Nicotinamide riboside uptake linked to metastasis and NAD... by JPLeRouzic on Monday November 14, 2022 @02:38PM (#33599721)
because NR provides extra energy to cells?
Re:Nicotinamide riboside uptake linked to metastasis and NAD... by gus_massa on Monday November 14, 2022 @04:19PM (#33601257)
It's slightly outside my knowledge are, so I'll try my best, but it may have some errors. Oversimplifying_

If you join two molecules of nicotinamide riboside with a phosphate you can make one molecule of NAD+.

When your cells burn sugar, they actually transform NAD+ into NADH, and later the NADH is "burned" with the oxygen to produce back NAD+ and make a few ATP molecules.

The ATP stores the energy for a short time, until that energy can be used for something useful, like moving your legs or making proteins.

The easy version in school is

  sugar + oxygen -> CO2 + energy
but there are like 50 intermediate steps to capture as much of that energy in a useful form. One of the intermediate steps uses NAD+, that is formed by two copies of nicotinamide riboside and a phosphate.
Re:Nicotinamide riboside uptake linked to metastasis and NAD... by JPLeRouzic on Tuesday November 15, 2022 @01:40AM (#33606021)
Thanks!