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A comment on A gut-derived hormone suppresses sugar appetite/regulates food choice Drosophila. Parent comment

Re:A gut-derived hormone suppresses sugar appetite/regulates... by anaisbetts on Sunday November 13, 2022 @11:26AM (#33584528)
A more appropriate drug for this is probably Ozempic/Wegovy (Semaglutide), or an even more effective version available in the US, Tirzepatide. I've personally been on the former and after 4.5 months, I've lost ~20% of my body weight
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Re:A gut-derived hormone suppresses sugar appetite/regulates... by bugfix-66 on Sunday November 13, 2022 @11:34AM (#33584614)
No, metformin is safe and has various health benefits.

Metformin seems to be almost a pure win, even for healthy people.

GIP analogues like semaglutaide are a different story, with real real risks and unknowns. For some people, with serious health problems, GIP analogues make sense. But generally you don't want to be taking them if you're healthy.

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Re:A gut-derived hormone suppresses sugar appetite/regulates... by bilsbie on Sunday November 13, 2022 @11:37AM (#33584660)
Aren’t those hard to get and then super expensive if you do quality?
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Re:A gut-derived hormone suppresses sugar appetite/regulates... by anaisbetts on Sunday November 13, 2022 @11:44AM (#33584736)
No idea, in the EU I pay ~85 EUR/mo
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