Only if you are completely clueless on what marginalization means, which by the rest of your comment, it appears you are.
It would make for a more substantive discussion if you explained why you disagree with my comment - could you elaborate further?
": to relegate (see relegate sense 2) to an unimportant or powerless position within a society or group"
https://www.merriam-webster.com/dictionary/marginalize
Trans people, especially trans women are treated poorly. They have less economic opportunity, have a high incidence of being victims of crime, and face violence from society.
Being successful in spite of being marginalized doesn't somehow magically make you no longer marginalized.
Just like there are successful Black people, but they still experience systemic and social racism. Success doesn't magically change that.
I'm guessing you don't believe in systemic racism though, so its probably a non-starter
The Bee's article is more broadly a commentary on how accolades intended for women are now going to men who identify as women - which rather undermines the point of having such awards in the first place. The humor is in inverting this:
"The Babylon Bee has selected Rachel Levine as its first annual Man of the Year. Levine is the U.S. assistant secretary for health for the U.S. Department of Health and Human Services, where he serves proudly as the first man in that position to dress like a western cultural stereotype of a woman."
Criticizing male dominance like this is very much a 'punching up' type of comedy.