Sure, absolutely, there are people out there who watch women in Iran get murdered for not wearing a Hijab, or watch the people of North Korea starve to death under a totalitarian dictator, and say "Yeah but the US isn't good either" and they're wrong. There is a bright clear line here, the US is a democracy with real institutions for holding the government to account, and the entities on the OFAC list aren't. If you want to support the totalitarian regimes of North Korea and Iran against the interests of the US fine. But let's call it what it is, you're providing aid to the enemies of freedom and democracy.