Sure. Pretty much most variants of looking for a change. It's fine if there are lots of things that you'd be open to that are different from what you're doing today, but you can tailor that for the company.

I've always had a pretty good idea when I've shifted companies (although in one case it was I want to do the same thing but with a solvent company). However, it's always been with people I knew. I've never had a real interview since grad school decades ago.