That the society is moving away from the concept of calling or vocation is also a problem. As a scientist (or physician or nurse or whatever) you are no longer rewarded for devoting your life to such things. You will not be supported (maybe even shamed for your enthusiasm or for failing in the reas of life that you are sacrifying), noone will watch your back, the administration will blame you for what they can, and you will not be paid overtime of course