Yes, I tried arguing with someone that it was actually more secure to run your Lambda without associating it with a VPC. If it doesn't need access to the VPC resources, it shouldn't be "run in" one. What can be more secure than having absolutely no access?
And I know I’m probably preaching to the choir. But one of the misconceptions I have to constantly fight is “we run our Lambdas in a VPC for security reasons”. (Lambdas are never “run in” a customer VPC)