They're looking for a pill they can patent, and then will demonize and do a fear campaign on the non-patentable options.

If the supposed anti-depressant effect of whatever specific molecule they claim doesn't induce relatively rapid nerve generation, opening up previously closed or blocked off pathways - that pruned off arguably due to trauma and lack of use - then they likely aren't as powerful as where the mystic effects come from; it's the temporary turning off, removing the ego mind from the algorithm of the mind/the mind's eye - allowing you to see reality very differently then you've been formed rigidly in beforehand; some tribes give Ayahuasca to their babies to keep them open as they develop, rather than letting trauma and/or natural processes lock them into more narrow behaviour and thinking patterns.