Not for most. I used a 16 GB iPhone SE with only a handful of apps for a while, but the biggest problem was the NY Times app where I get my news. Its cache will grow without bound, and once it would get to ~2 GB every few weeks I'd have to uninstall and reinstall the app to delete the cache. (Later on they created an option in settings to delete the cache.)

I thought the 16 GB phone would work for me since I keep everything in the cloud -- no downloaded photos/music/nothing. Nope, and it was all because of app caches. I got so sick of having to uninstall and reinstall some app literally every week to clear its cache.