These are organismal phenotypes which have no direct correlate to molecular phenotypes (because they are complex and caused by entirely nontrivial developmental processes). Even if you knew the proteins involved you couldn't craft a realistic model that explained the observed organismal trait from the protein variations using any amount of existing scientific methods.

Obviously this isn't true for some diseases, such as simple mendelian diseases caused by single SNP changes.

I worked in the field for decades and very little progress has been made mapping genotype to complex organismal phenotypes or appreciating how complex development processes are affected by collections of mutations. This specific research, even if wildly successful, wouldn't really have impact on any significant diseases.