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Re:Ask HN: What interesting problems are you working on? by O__________O on Friday September 16, 2022 @12:38PM (#32868654)
For anyone interested, found following blog post on OP’s website, which is linked to from their HN profile:

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How to make DNA synthesis affordable

https://keonigandall.com/posts/affordable_dna_2.html

Re:Ask HN: What interesting problems are you working on? by waiquoo on Friday September 16, 2022 @01:03PM (#32868988)
Having worked at the largest synthetic DNA manufacturer (at least they were, I think they still are)... a lot of his information is just wrong. There is a huge incentive to lowering the cost of producing oligos and synthetic genes. This is actually a very interesting time in the space (shoutout AnsaBio).

I encourage him to continue explore new ways of making DNA, but understanding the market is very different from building off an expired patent.

Re:Ask HN: What interesting problems are you working on? by koeng on Friday September 16, 2022 @07:11PM (#32873227)
I’ve spoken to the CEO of Ansa bio about this topic and they aren’t focused on lowering prices, but increasing what can be built.

I would like to know what specifically you think I am wrong about, though. Always happy to improve my thinking.