You talk like cryptocurrencies are a valid alternative, even though they have a terrible UX that makes their adoption in the real world near non-existent. Hell, losing or getting your private keys stolen could also nuke your business. Yes, every option comes with its issues, and so far cryptocurrency's issues far exceed other options for businesses.

It will be a solution for everyone running a legal business (i.e. one that doesn't impose significant negative externalities on others). Making life harder for criminals is a feature not a bug.

As a business you'd have to pay taxes, deal with customer support, accept multiple currencies, etc, so even when accepting cryptocurrency payments it's likely you would use a payment processor. Those payment processors would probably be just as reliable as the fiat ones... (hell they'll probably be the same companies)

Remember, Stripe is not known to be reliable, just convenient. People will go for the convenience with cryptocurrency as well, there is no reason to believe otherwise.