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Re:Pre-exposure to mRNA-LNP inhibits adaptive immune respons... by ttpphd on Tuesday September 13, 2022 @01:10PM (#32827162)
No! No!

No!

We already know we made the right choice because the alternative was 20 million more dead. This "time will tell" bullshit is ridiculous. We swerved the car to avoid crashing it head on into a wall, and yes you might have whiplash but there is no honest room for second guessing the decision not to drive the car into the wall at full speed.

Re:Pre-exposure to mRNA-LNP inhibits adaptive immune respons... by spookthesunset on Tuesday September 13, 2022 @01:17PM (#32827290)
Where do you get this “20 million more dead” figure from? Some model?
Re:Pre-exposure to mRNA-LNP inhibits adaptive immune respons... by OrangeMonkey on Tuesday September 13, 2022 @01:37PM (#32827604)
I'm sorry but that is not how science works. We will be studying this for years and changing healthcare policies as a result of this. Its not "second guessing bullshit" its looking at what happened, the results of it, and changing our future actions accordingly.

There is an entire branch of study - one which I work in - whose entire job is to run either observational studies or post-hoc studies using real world data to find out if something had an impact, a positive impact, negative impact, and what the likelyhood of your own study being correct is.

If you think this is 'done' and we shouldn't revisit this to see what we did well / did poorly then that is as anti-science as they come.

Re:Pre-exposure to mRNA-LNP inhibits adaptive immune respons... by ttpphd on Tuesday September 13, 2022 @02:30PM (#32828394)
This is a non response because you are not considering the counterfactual properly. How will future studies factor in the millions of lives saved?
Re:Pre-exposure to mRNA-LNP inhibits adaptive immune respons... by OrangeMonkey on Tuesday September 13, 2022 @02:59PM (#32828747)
With all due respect, further tests, research, and outcome analysis on the people impacted by our choices will be how we understand our response and what we should have done differently.

You are lumping every response to the pandemic together and appear to be saying "you can't judge this, would you rather millions have died??" - well no, but thats not the question either. Instead "We did things to respond to the pandemic, some good some bad. What was good and what was bad."

This will happen. Saying "NO NO NO" is not going to stop that or help it.