It seems that there's a very pessimistic trend with regards to estimating the feasibility of engineering human biology for inhabiting outer space. Everyone just wants to let AI do it. I think this is because the progress of biotech has been so glacial. This is largely due to regulation. China will probably change the rules around at some point to allow for more flexibility here, with lots of moral outrage and handwringing in the west, and speed off into the future.