I don't thin it would even rule out non-local hidden variable interpretations of QM such as de Broglie–Bohm theory <http://en.wikipedia.org/wiki/Bohmian_mechanics>, since these accept the wave function as real but posits that there is also an actual configuration of the universe, which evolves in a manner that is guided by the "pilot wave".
"On a related, but more abstract note, the quantum state has the striking property of being an exponentially complicated object. Specifically, the number of real pa- rameters needed to specify a quantum state is exponen- tial in the number of systems n."
This is an oblique way of saying that (quantum) reality consists of many (classical) worlds.
In fact, there are logically only three possibilities:
1. The quantum wave function comprises zero classical realities, i.e. what we call classical reality is not real but some kind of illusion. This is actually a scientifically tenable point of view. See http://arxiv.org/abs/quant-ph/9605002, particularly section VI.
2. The quantum wave function comprises one classical reality, i.e. Copenhagen. This is not any more a scientifically tenable point of view.
3. The quantum wave function comprises multiple classical realities, i.e. many-worlds is (are?) physically real.
Personally, I subscribe to option 1.