Seconded. My working state is crucial and keeps me on track. For someone with ADD, needing to overcome the inertia of setting up all my apps just the way I left them every single day would be catastrophic for my productivity. I refuse to reboot more than once a month, and only then if an OS update requires it.

The year is $CURRENT_YEAR, needing to reboot a system should be regarded as a last resort and a relic of the past. No matter how much effort you dump into making apps remember their state when they're closed, it will always be strictly inferior to just dumping RAM to disk.