I have had good trips and bad trips on a variety of highly psychedelic substances, and I've had a lot of those trips. Trying to engineer the trip out of the drug to get a desired psychoactive result free from pesky side effects like not being as grounded to reality for a while is absolutely missing the forest for the trees. Not to say that it can't produce some benefit but it's leaving a lot of unexplored potential on the table, largely in deference to failed puritanical ideals about recreational drug use.