I wouldn't see how. AIUI, DeFi loans are over collateralized. It's appears to like taking out a second mortgage on your home. You make payments or the collateral disappears.

The only benefit of this I can see is converting tokens to cash as a hedge against a crypto crash. If you pay off the loan and the token price continues to grow, you get all your tokens back and it only cost you the interest. If the token price crashes, well you already have the cash, so you can default on the loan and the only collateral is worthless tokens.