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Re:Two decades of Alzheimer’s research was based on delibera... by nradov on Sunday July 24, 2022 @10:12AM (#32213686)
Ioannidis JPA (2005) Why Most Published Research Findings Are False. PLoS Med 2(8): e124. https://doi.org/10.1371/journal.pmed.0020124
Re:Two decades of Alzheimer’s research was based on delibera... by epistasis on Sunday July 24, 2022 @10:31AM (#32213842)
This paper would be more relevant if most science came down to evaluating a single p-value. Perhaps there are some fields of science where that is true, but I have not encountered them. I mostly look at molecular biology and infectious disease. Clinical trials in medicine come down to a single p-value by design, but don't fall prey to what he's talking about.