I've seen much the same problems when trying to programatically construct a large number of objects using the (low-level) Python API. If this kind of optimization improves throughput of those APIs that would be a major enabler for work that I want to do.

Otherwise I'm side-tracked looking for relatively awkward SIMD-style programming (e.g. Geometry Nodes) as a workaround for "CRUD" operations being too slow. Can't be just me...