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Re:Air France announces end to research monkey transport by duckmysick on Sunday July 10, 2022 @04:31PM (#32048690)
A comment by bsdz links a research paper and says that a computer model for cardiotoxicity has higher accuracy than animal models. The paper title mentions in silico as well.

Are those the same things you're talking about or is there something I'm missing. I'm not that familiar with drug development.

https://news.ycombinator.com/item?id=32048391

Re:Air France announces end to research monkey transport by oaktrout on Sunday July 10, 2022 @06:29PM (#32049811)
The paper linked by bsdz checks for one specific cardiac side effect, it is not anywhere close to being a model for cardiotoxicity as a whole, a very important distinction.
Re:Air France announces end to research monkey transport by duckmysick on Sunday July 10, 2022 @06:36PM (#32049863)
Ok, that makes sense.

Is there a meta analysis of such models?

Re:Air France announces end to research monkey transport by oaktrout on Wednesday July 13, 2022 @07:58PM (#32090264)
I'm not sure tbh, this really isn't my area of expertise. Sorry, I was hopeful someone more knowledgeable would reply.