In my experiences between Asia and Latin America, if you're going to be drinking alot on whatever occasion, it better be with a lot of food. Even Eastern Europe for instance with their famous straight vodka shots have something (In Russian, at least) called 'zakuski' which means 'Something to bite after', which means after each shot you eat a pierogi or whatnot [1]. It really does a lot to dampen the after-effects beyond what water is capable of.

You can get at most bars a full meal for around 5$ or sometimes even less. Cocaine isn't very popular with the locals, again especially the younger ones, as it's caused us a lot of societal problems (Stuff like people who don't even touch it ending up tied up in narco violence chiefly... It's just the worst vibes on top of that).

[1] https://en.wikipedia.org/wiki/Zakuski