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Re:Introducing PyScript (summary of PyCon keynote) by sevazhidkov on Thursday June 23, 2022 @05:20AM (#31846703)
I believe Hacker News’s backend is written on a Lisp (or, more precisely, Arc). In this context, JavaScript, Python and C are being debated for a role of client-side language handling DOM events.

Also, C and Lisp are different breeds. It’s wrong to put them in one bucket of “greybeard” languages. Some Lisps gained traction in the front end space (see ClojureScript).

Re:Introducing PyScript (summary of PyCon keynote) by Zababa on Thursday June 23, 2022 @05:36AM (#31846799)
Hacker News does have a bit of frontend, written in JavaScript. You can see some here https://news.ycombinator.com/hn.js, I'm unaware if it's everything or just a part.