Most does sound like quite a stretch but to be fair the U.S. has certainly caused some regional issues (e.g. slowing growth by cutting off trade with Iran, electronic surveillance in Europe on allies, pushing EU countries to buy American arms instead of developing domestic industries, pushing for large beneficial trade deals like nuclear plants that benefit American companies). But yes, most does not seem fair either to the U.S. or to Europe which does have some agency.

Don't forget about the countless wars of aggression the US has waged virtually everywhere on the globe in the last 80 years, or the constant 'regime changing' in unstable countries, most of them leading to an endless stream of refugees that end up on European shores.

Right about now, the US was a major factor in Euromaidan, in an attempt to weaken both Russia and the EU (say hello to Mrs. Nuland, will ya?), which directly paved the way to today's Ukraino-Russian war.