Would one be able to tell a difference at a much higher dosage? What about when compared to an equivalent dosage of another CNS like methylphenidate or cocaine?
I never dared risk much higher dosages, so I wouldn't know.
> What about when compared to an equivalent dosage of another CNS like methylphenidate or cocaine?
In my experience, one can definitely tell the difference between (meth)amphetamine and methylphenidate / cocaine, at any dose. They are by no means that different, though, and I wouldn't be surprised if a person with no previous exposure to either would struggle to do so. Other CNS stimulants, like nicotine and caffeine, are more obviously different.
This is all purely anecdotal, though I have skimmed studies which also claimed as much, so those might be worth looking into.
Have you ever tried both, though? Once you factor out the faster uptake due to that methyl group, it's essentially impossible to tell which is which at equivalent, medicinal doses.