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A comment on Gene Therapy Reverses Biological Aging by Six Years.

Re:Gene Therapy Reverses Biological Aging by Six Years by getpost on Wednesday June 01, 2022 @10:08AM (#31582001)
It's been possible to increase growth hormone by injection for a couple decades now, and I thought there was a cancer problem[0].

Also, there's the drive for homeostasis. In my own experiments with dietary supplements, I get a short term boost due to the supplement, but the body gradually re-configures itself accordingly, so there's no long term benefit. e.g., caffeine[1]

[0] Growth Hormone's Links to Cancer https://pubmed.ncbi.nlm.nih.gov/30500870/

[1] Chronic Caffeine Alters the Density of Adenosine, Adrenergic, Cholinergic, GABA, and Serotonin Receptors and Calcium Channels in Mouse Brain https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437321/

EDIT: Author has a wikipedia article and a website. https://en.wikipedia.org/wiki/Brian_Hanley_(microbiologist) https://bf-sci.com/

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Re:Gene Therapy Reverses Biological Aging by Six Years by tayne on Saturday June 04, 2022 @11:19AM (#31621334)
You point to one example of homeostasis and therefore we should just give up on all medicine? That’s like someone putting down the idea of vaccination because they developed a coffee tolerance. The human body is complicated and diverse and homeostatic forces aren’t omnipresent or present at the deepest mechanistic levels.
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