Unfortunately unlikely. Shared nothing architecture works with messaging. So threads send each other messages like "give me the contents of that key" or "update this key". Operations like SET/GET will require a single message hop. Operations like RENAME require 2 hops. Transactions and Lua scripts will require number of hops as number of operations in the transactions. When it's in the same process - the latency penalty in negligible. But between different machines - you will feel it. But who knows, AWS already have very cool UDP-like protocol with very low latency... if this will become the standard inside cloud environments maybe we can create a truly distributed memory store that spans multiple machines transparently.