Last time I used bloom filters, was when I had MANY BIG files containing dns queries and responses. Instead of putting the data in a database and create indexes (project would not the defend the cost of having a database), I created a bloom filter per file. Whenever I needed to search for a query or response, I would quickly know which files I needed to look in.

I think I used this module https://github.com/remram44/python-bloom-filter