I recently published a paper [1] that I wrote using TeXmacs and then converted to LaTeX before publishing it on arXiv. The conversion was not completely seamless: it took me around 2 hours to tweak it to my liking. However, I feel that I would not have been able to finish the paper without TeXmacs. Honestly, 2 hours was a fair trade-off. Probably I would have spent a similar amount of time aligning equations by hand once I was done with writing. Texmacs -> LaTeX conversion actually made that part more streamlined.

[1] https://arxiv.org/abs/2205.09851