With firefox and NoScript, you can whitelist the specific JS you need to make those sites work. You do it one time for a site you know you'll come back to often, and then you're done. In my case for example I whitelisted the scripts at old.reddit.com and redditstatic.com, and leave everything else blocked by default and it works fine for my needs (reading comments).

The fact that there are a handful of very frequently used websites that use JS doesn't make it impossible or overly burdensome to take sensible steps to limit which scripts you allow.

I use amazon in firefox with NoScript without issue, and while amazon gets to run some scripts, none of the JS at amazon-adsystem.com ever runs in my browser.

Youtube wants to load JS from over a dozen different places, but you only need to allow a couple to get videos to play (I personally prefer to just download yt videos to disk and watch them in VLC avoiding that issue entirely)