Wordpress. Worked in company using Woocommerce for their e-commerce solution, It was profitable at that. That is if you want a quick and simple solution. If you want something less turnkey and more flexible but more tasking, Django or Laravel is a good option.

Don't overcomplicate things, simplicity is often underrated on the web side of development. This is coming from a guy who writes low level embedded c and c++ on a daily basis.