AI. There are things it will do extremely well, but life will go on. Despite all the chainsaws and cranes, humans are still cutting wood and lifting bricks. Despite all the robotics, humans still operate production lines. Some fields will get hit hard by AI (e.g. copywriting, ghost writing, stock images).

At some point we'll probably see new tools emerge, the kind of things that emerge like Facebook. I'd bet on a change in gaming where the games can give a lot more agency to players, rather than being just a storytelling medium or skill based.

Creative jobs will morph. Writing will be like product management or sculpting, where the author has a vision and context. Art may be like directing or DJing.