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A comment on Long-term benzodiazepine use causes synapse loss and cognitive deficits in mice. Parent comment

Re:Long-term benzodiazepine use causes synapse loss and cogn... by tsol on Sunday May 15, 2022 @05:47AM (#31386453)
Are you being treated with chronic pain by any pain killers? I've heard this before, but it's not exactly as you put it. Chronic opioid use leads to sensitization to pain. This doesn't mean it is equivalent to the pain being treated. In my experiencing minor sensitization to pain in exchange for treating debilitating, disabling, and depression-inducing pain is an amazing trade. I'd do it again without a second thought. It gave me the ability to go to school and start a career, as opposed to being permanently disabled
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Re:Long-term benzodiazepine use causes synapse loss and cogn... by jnovek on Sunday May 15, 2022 @10:52AM (#31387909)
The main thing I’ve learned over the last few years is that people without chronic pain have absolutely no understanding or frame of reference for what people with chronic pain experience.

I would happily trade 10 to 20 years off of my life to live the remaining ones pain-free and functional.

Edit: One of the most frustrating things I experience are doctors who don’t understand topics that guide “no tolerance” policies; for example, they are aware they hyperalgesia exists — much like the GP — but don’t really know what it is or what it’s like for the patient.

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