Re:Faecal transplants reverse hallmarks of ageing
by bawolff on Friday May 06, 2022 @11:13PM
(#31291856)
> For example, patients who had undergone antibiotic exposure within a 6 month period preceding their admission to the ICU had a 20% increase in mortality rate.
That seems like a very obvious case of correlation vs causation (people who need medicine are more likely to die than those who dont)
Another study [1] I just found showed that older women who had been exposed to antibiotics for => 2 months had increased risk of all-cause mortality and cardiovascular mortality (hazard ratio 1.49). Interestingly, if they had also been exposed to antibiotics in middle-adulthood, their mortality rate was even higher; which may suggest that antibiotic exposure permanently impairs the microbiome. Paper's conclusion: "Long-term use of antibiotics in late adulthood may be a risk factor for all-cause and cardiovascular mortality. The unfavorable effect of antibiotic exposure for subsequent risks of deaths due to chronic diseases needs to be considered."
[1]: https://pubmed.ncbi.nlm.nih.gov/31842690/