I can see that happening. Interestingly though, while I'm a right handed person and use mouse with my right hand, I use the trackpoint with my left hand! It actually thus helps prevent RSI for me - I get to mix it up and switch my hands :). I also find that it's a very different position - I think stretching right thumb to hit left button is harder than using left thumb to hit left button, which is just naturally resting there (understanding of course these can be remapped:).