For example, Down syndrome can be practically eradicated by selectively aborting aneuploid embryos. Of course, the embryo cannot consent, and while the parents can, institutional pressures can be put on them to make them change their mind.
Countries like Iceland and Denmark abort almost all Down syndrome embryos. This article in The Atlantic does not seem to be completely OK with that, and The Atlantic is pretty representative for East Coast liberal viewpoints.
https://www.theatlantic.com/magazine/archive/2020/12/the-las...
Which is a weird and arbitrary location to draw the line considering how those institutions tend to lean on other issues, or even the same issue in a slightly different context.
I mean, technically the person born with Down Syndrome would be incapable of consenting on their own life decisions after they were born, right?
Then there are mosaic cases, which are in the middle between a full Down Syndrome and normalcy. In mosaic cases, only a certain percentage of cells is afflicted. People with mosaic aneuploidies can often lead fairly normal lives.
If, in 2030 or 2050, it will be possible to use CRISPR or another newer technology to edit out detrimental alleles out of someone's DNA safely, the end effect on the genetic pool of humanity is going to be very similar to the one that eugenicists tried to achieve via more primitive means.