Covid spike protein induces cognitive deficit and anxiety-like behavior in mice

Re:Covid spike protein induces cognitive deficit and anxiety... by pydry on Sunday April 03, 2022 @06:45PM (#30901505)

My first thought as well. I never caught covid but social isolation definitely induced anxiety and cognitive deficit in me.

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Re:Covid spike protein induces cognitive deficit and anxiety... by fffobar on Sunday April 03, 2022 @06:57PM (#30901587)

What if it was caused by both?

I'm in your shoes, and pondering this very question.

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Re:Covid spike protein induces cognitive deficit and anxiety... by forum_ghost on Sunday April 03, 2022 @08:42PM (#30902278)

It is both.

Social isolation does cause depression and anxiety, as social interaction is a very well proven anti-depressant.

Covid is also known to destroy your sense of smell. The olfactory bulb. which is neural tissue in your nose, goes right into your brain, and has no protection from blood brain barrier...because it doesn't have it.

Covid is neurotoxic. Isolation does cause depression. Both are true.

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Re:Covid spike protein induces cognitive deficit and anxiety... by IdEntities on Sunday April 03, 2022 @09:33PM (#30902536)

"SARS-CoV-2 attacks olfactory mucosae but spares the olfactory bulb": https://www.cell.com/cell/pdf/S0092-8674(21)01282-4.pdf

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Re:Covid spike protein induces cognitive deficit and anxiety... by forum_ghost on Monday April 04, 2022 @08:09AM (#30905697)

That doesn't mean the brain is spared. Covid does get into the brain, and CNS positivity is correlated with olfactory mucosa positivity. Something we've known since autopsy report after autopsy report since 2020. Two years now.

Fig 1b, 1c. Fig 5.

https://www.nature.com/articles/s41593-020-00758-5

"Presence of intact CoV particles together with SARS-CoV-2 RNA in the olfactory mucosa, as well as in neuroanatomical areas receiving olfactory tract projections"

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