Re:The human genome is, at long last, complete
by sterlind on Sunday April 03, 2022 @12:13AM
(#30894371)
what do you mean by "~1 SNP?" one de novo amino acid substitution? or inherited? we have millions of variants.
the redundancy of codons - several codons code for most amino acids, and one-base-pair changes are often synonymous or will code for similarly-charged residues - provides some protection.
on the other hand, if you have a mutation in, say, a non-coding intronic splice site, that can really fuck a protein up. I got unlucky there.
the redundancy of codons - several codons code for most amino acids, and one-base-pair changes are often synonymous or will code for similarly-charged residues - provides some protection.
on the other hand, if you have a mutation in, say, a non-coding intronic splice site, that can really fuck a protein up. I got unlucky there.