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A comment on Phenethylamines I Have Known and Loved (1991). Parent comment

Re:Phenethylamines I Have Known and Loved (1991) by jaminal on Friday April 01, 2022 @12:51AM (#30875299)
This is very likely false; a myth perpetuated from the war on drugs combined with people taking unknown, untested substances in recreational settings.

If they experienced serotonin syndrome it was quite easy to just point at the reported seratonergic substance that had been ingested (and which also may not have been present at all, depending on the source).

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931730/

[ Parent | on HN ]
Re:Phenethylamines I Have Known and Loved (1991) by eurasiantiger on Friday April 01, 2022 @08:23AM (#30877450)
The worst cases are likely from interplay with other medications or simply overheating.

However, the same is repeated in literature about plain methamphetamine, not just methylene-dioxy-methamphetamine, so I would not entirely trust the current state of science on this.

[ Parent | on HN ]
Re:Phenethylamines I Have Known and Loved (1991) by jaminal on Saturday April 02, 2022 @10:04AM (#30888374)
It’s repeated for lots of medications where it could never happen. SS is widely misunderstood even in the medical community.

I trust specific doctors who specialize in psychedelic medicine and psychiatry who have deep understanding of the metabolic pathways and pharmacokinetics of these substances.

https://www.pharmacytimes.com/view/serotonin-syndrome-myths-...

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8820588/

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