Re:Old Spleens Suck (2021)
by outworlder on Saturday March 26, 2022 @12:17AM
(#30809194)
> You should read up on the thymus next. That one is super important and is also implicated in aging.
That one seems to self-deactivate with age.
Indeed. The thymus is responsible for much of our immune cell production, but it shrivels away to nothing by our elderly years.
It's unfortunate, because our responses to immune challenges - including cancer - diminish with age.
Spleens are essentially large bags of blood and immunological pulp, and the reason they evolved this way is because they act as a filter against bloodborne pathogens. They host a diverse but specialized collection of immune cells, such as macrophages, and have a truly unique and interesting role in overall health.
You should read up on the thymus next. That one is super important and is also implicated in aging.