For all intents and purposes there is only one instance of your business code. It is a single process. And you do whatever you want.

However, this is not a problem at all. In Go you would have to get out of your way to share information between user agents just like you would have to do in PHP.

Intentionally writing to and reading from a global variable is the exact same as intentionally writing to and reading from your MariaDB instance.

I have no clue why you would render this process problematic. Maybe in Python everything is a global?!